Senior Director, Translational Medicine and Clinical Biomarkers

Senior Director, Translational Medicine and Clinical Biomarkers Own the translational science that decides which patients get treated and how — leading biomarker strategy across Nurix’s entire oncology and immunology portfolio. This is a senior, portfolio-level role with direct influence on trial design, dosing decisions, and executive strategy from day one. The Opportunity Own and evolve the clinical biomarker strategy across Nurix's full clinical portfolio, setting priorities that inform patient stratification, response prediction, and resistance mechanisms for multiple concurrent programs (not a single franchise or indication). Provide scientific interpretation of biomarker data, informed by a strong understanding of cell and tumor biology, molecular biology, inflammation, and immuno-oncology, helping translate those insights into patient-selection, dose-selection, go/no-go, and program-level development decisions. Direct the build-out and governance of biomarker assay capabilities across the portfolio, including assay qualification standards, platform strategy, and vendor/CRO oversight, to ensure consistent, scalable execution across programs rather than one-off, program-specific solutions. Set the strategic direction for evaluation and adoption of novel biomarker technologies and platforms, positioning Nurix's biomarker capabilities ahead of program needs rather than reacting to them. Lead and integrate cross-functional, matrixed teams spanning clinical development, research, regulatory, and external collaborators, ensuring biomarker data is embedded in clinical development plans and regulatory strategy at the portfolio level. Provide senior scientific and strategic input into clinical trial design across programs, influencing go/no-go and dose-selection decisions where biomarker data is a critical input. Directly manage and develop at least one direct report, with responsibility for hiring and scaling the team as pipeline needs grow. Act as a key scientific st