Scientist I, Bioanalytical

Scientist I, Bioanalytical Help drive Nurix’s drug discovery programs by turning complex biological samples into the high-quality bioanalytical data that guides decisions. You will develop and run LC-MS/MS assays for targeted protein degrader candidates and work closely with pharmacology, chemistry and biology teams. Position Description Nurix Therapeutics is searching for a motivated Scientist I to join our Bioanalytical team. The successful candidate will contribute to the bioanalytical efforts to support Nurix drug discovery programs involving in vivo and in vitro studies. The primary responsibility will be to conduct quantitative bioanalysis for in vivo samples. The scope of the daily responsibilities for this position includes, but is not limited to, developing bioanalytical methods, quantitating drug candidates and their metabolites, endogenous biomarkers in biological matrix (e.g. blood, plasma, tissues, tumor, CSF, etc.), and reporting high-quality data. The successful candidate will have extensive experience in bioanalytical method development and sample analysis using LC-MS/MS and other analytical techniques. The Opportunity Provide bioanalytical support for in vivo PK, PK/PD, efficacy studies, non-GLP toxicology and in vitro studies Conduct bioanalytical method development and qualification to support drug, metabolite and biomarker analysis Independently develop LC-MS/MS methods to quantitate small molecules in in vitro and in vivo samples and execute sample analysis Independently operate, troubleshoot and maintain LC-MS/MS and analytical equipment Participate in multidisciplinary project teams and partner closely with other departments, including pharmacology, chemistry and biology to understand bioanalytical needs for PK support Maintain accurate and detailed laboratory notebooks Ability to think and plan strategically, and excellent interpersonal skills and ability to work in a team environment What You’ll Bring BS or equivalent with 10 or more years’