Senior Scientist / Principal Scientist, Induced Proximity

Senior Scientist / Principal Scientist, Induced Proximity Help shape Nurix’s induced proximity strategy beyond targeted protein degradation. In this hands-on role, you’ll design and run the assays that validate targets, characterize mechanisms and inform go/no-go decisions, working alongside chemistry, biology and biochemistry partners. It’s a chance to grow your scientific, and potentially leadership, experience in a fast-evolving area of drug discovery with direct exposure to platform-level strategy. Position Description The Opportunity Nurix Therapeutics, Inc. is seeking a motivated scientist to support and help execute the non-degradative induced proximity research strategy. This individual will contribute hands-on scientific expertise to programs beyond targeted protein degradation, helping advance target validation, mechanism characterization, and candidate optimization efforts. Working closely with the Senior Vice President of Induced Proximity and cross-functional partners in chemistry, biology, and biochemistry, this person will help translate strategic priorities into experimental plans, generate and interpret data that inform go/no-go decisions, and contribute ideas on emerging modalities and technologies worth exploring. This is an opportunity to grow scientific and possibly future leadership experience within a fast-evolving area of drug discovery, with direct exposure to strategic decision-making at the platform level. Design, execute, and troubleshoot experiments at the bench; building and running biochemical, biophysical, and cell-based assays to interrogate induced proximity mechanisms and drive program decisions Contribute to identification, validation, and prioritization of targets amenable to induced proximity approaches (protein sequestration, gene regulation, stabilizers, and related mechanisms) Evaluate and integrate new and emerging induced proximity modalities into the strategic roadmap Partner with computational/structural biology to advanc